Karen M. Puopolo, M.D., Ph.D. is a neonatologist who specializes in neonatal infectious diseases. Dr. Puopolo is an Associate Professor of Pediatrics on the faculty of the University of Pennsylvania Perelman School of Medicine. She is a member of the Division of Neonatology at The Children’s Hospital of Philadelphia, and Section Chief for Newborn Medicine at Pennsylvania Hospital. Dr. Puopolo received her undergraduate degree in physics from Yale University, and went on to obtain her M.D. as well as a Ph.D. in molecular physiology from the Tufts University School of Medicine in Boston. She completed Pediatric residency and Neonatal-Perinatal fellowship training at Boston Children’s Hospital. Dr. Puopolo was appointed to the faculty of Harvard Medical School from 2000-2014 where she was a physician and researcher at the Brigham and Women’s Hospital and the Channing Laboratory investigating mechanisms of virulence in Group B Streptococcus. Her current research focuses on neonatal sepsis epidemiology and risk assessment. She is currently funded by the National Institutes of Health and the CDC to study the impact of neonatal antibiotic exposures on the newborn and early childhood microbiome, and on infant and early childhood growth. Dr. Puopolo is a member of the American Academy of Pediatrics Committee on the Fetus and Newborn and serves on the Editorial Board for Pediatrics.