Thank you so much for the invitation. It was my pleasure to be part of the conference. More research and awareness for GBS invasive disease are still needed.

Great work! Mouse models are so important as we study disease. Thank you for your contribution!

Thank you for your comment. You are right. The values drop till bacteria were no longer detected. Mice are not natural hosts for GBS. Indeed, models of chronic colonization with GBS in the vaginal mucosa requires the use of estradiol to synchronize the mice in the estrus phase of the reproductive cycle. Have in mind that this is not in the context of pregnancy. We did not use such treatments, as our goal was to have colonized females during pregnancy. Although we didn’t check, we believe that without estradiol the mice immune system will eventually clear bacteria.

Excellent presentation! You mentioned in your presentation when showing the lung pathology graph (16:50ish) about the throat in humans being a good site for GBS detection in childhood. Could the pups have acquired GBS in their lungs from oral contact with each other or from nursing?